Preheat oven to 425 degrees F. Grease a 3-quart (13x9) casserole dish with nonstick cooking spray and set aside.
Pat chicken dry with paper towels. If needed, lightly pound the chicken breasts to an even thickness. Arrange in the baking dish. Season to taste with salt and pepper.
In a small bowl, combine mayo and Parmesan cheese. Spread evenly over the chicken. Sprinkle with breadcrumbs and Italian seasoning.
Bake in the preheated oven for 18-22 minutes, or until juices run clear and the internal temp registers 165 degrees.
Remove from the oven and rest for 5 minutes. Garnish with fresh minced parsley before serving.